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  • Medical industry

    Pharmaceutical manufacturing industry refers to the industry that transforms resources (materials, energy, equipment, tools, capital, technology, information and human resources) into medical industrial products and consumer goods for people through processing and manufacturing process according to market requirements. Pharmaceutical manufacturing industry includes seven sub industries according to national standard of “Classification of National Economic” (GB / T4754-2002): manufacturing of chemical raw materials, manufacturing of chemical preparations, processing of Chinese herbal pieces, manufacturing of proprietary Chinese medicine, manufacturing of veterinary drugs, manufacturing of biological and biochemical products, and manufacturing of sanitary materials and medical supplies.

    There are thousands of pharmaceutical enterprises in China, which have the production capacity of more than 1500 kinds of BPC. In 2009, total output of China was 1.936 million tons, which was the largest BPC exporter in the world.

    High investment, high consumption, high pollution and high emission

    Low output, low benefit, low concentration and low technology content

    Industrial characteristics

    Small scale:

    Large quantity and repeated products;

    Technology content of products is low, research and development ability of new drug is low, and economic benefit is low.

    Although GMP and GSP certification have eliminated a number of backward enterprises, the problems of large quantity, small scale, scattered and disordered pharmaceutical enterprises in China have not been solved fundamentally. Leading enterprises with international competitiveness are very scarce.

    Production and pollution links of industry

    Air pollutants in pharmaceutical manufacturing industry in China

    Pharmaceutical dust particles: produced from crushing, screening, filtration, mixing, drying and packaging in pharmaceutical production process;

    Volatile organic compounds: produced from the process of extraction and separation, solvent distillation recovery, transportation and storage of production processes;

    Fermentation tail gas: CO2, water vapor and part of fermentation metabolites produced by fermentation process;

    Acid and alkali waste gas: process of using hydrochloric acid and ammonia water to adjust PH value and other values will be volatilized partially;

    Odor: produced from extraction workshop of traditional Chinese medicine and extraction pharmaceutical enterprises, and animal room of bioengineering pharmaceutical enterprises

    Production process and sewage discharge of fermentation pharmaceutical products

    As an important way of technical drug manufacturing, production characteristics of fermentation are basically similar, which includes the steps of strain screening, seed preparation, microbial fermentation, fermentation liquid pretreatment and solid-liquid separation, purification, refining, drying, packaging and so on.

    Production process and sewage discharge of chemical synthetic products

    Production of chemical synthetic drugs takes chemical raw materials as the starting reactants. Intermediates are synthesized by chemical synthesis, and then drug structure is modified to obtain target product. Final product is obtained by de-protection, extraction, refining and drying.

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